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Rare Hib disease increases in Minnesota

Is the anti-vaccine movement to blame?

As the ultrasound tech spread the cool gel over her swollen belly, Brendalee Flint held her breath. Would it be another boy? Or would she finally get the daughter she'd always wanted? She'd be happy either way, she reminded herself for the umpteenth time.

Flint peered at the strange white shape on the black monitor. Even after three kids, the image still amazed her—watching the heartbeat was so cool. The ultrasound tech pointed out the lungs, the tiny hands, the little brain. The tech waited patiently. There! Now she could see. It was a girl.

Flint squealed. She wanted to go out and buy everything girly and sweet. To prepare for the baby's homecoming, Flint bought a purple dress and a matching headband and handbag.

Julieanna rushed into the world in October 2006, and came home three days old and already owning a purse. Her parents beamed, her aunties doted, her grandfathers cooed. She was the 15th grandchild to join the Flint family—but she was only the second girl.

Julieanna grew fast. Strong and chubby, she was a bundle of delight capped with dark hair and wide blue eyes. Her big brothers—Nicky, Alex, and Chris—pampered and adored her. "Julie," "Juju," "Jujubeek," "Jujubear," the family called her.

When Julieanna was 15 months old, her brother Chris called their mother at work because the baby was throwing up. Flint rushed from her job at Applebee's in Delano to her home in sleepy Watertown, a village set along the gentle Crow River.

By the time Flint arrived home, the situation had improved. The baby was running a slight fever but wasn't vomiting. A product of a family that believed in letting nature toughen the constitution, Flint gave the baby Tylenol and put her to bed.

The next day, Julieanna woke up puking, and her temperature began to rise. Flint called the office of Heidi Wuerger, her family doctor.

"It sounds like the flu," the nurse said. "Give her Tylenol."

Flint complied and kept a careful watch on Julieanna all day, feeding her liquids to flush out the illness, cooling her body with a wet washcloth.

The following day, Flint undid the baby's diaper and caught a whiff of something unusually pungent. Julieanna's urine was the color of orange juice, and its odor reminded Flint of the ammonia smell of the nursing home where she worked as an aide. As the day wore on, Julieanna refused to eat or drink.

Early the next morning, Flint awoke with a start: Julieanna was screaming—a shrill, sharp wail. Flint held Julie close, and the baby relaxed and dropped immediately to sleep. Flint shifted the little girl away from her body, and Julieanna awoke and screamed again. Flint pulled her close and the baby instantly fell back to sleep. Flint held Julieanna for hours. When the baby's temperature soared to 104 degrees, Flint called the doctor and made an appointment.

She put Julieanna in a bath to cool her. The little girl slumped against the back of the tub, as if she'd forgotten how to sit up on her own. Flint ran cold water over Julie's hair. The little girl held her head ramrod straight and her neck stiff. Her blue eyes veered left to meet Flint's, and the mother read an expression of terror in her baby's eyes. Flint pulled her daughter out of the tub, toweled her off, and rushed to the emergency room at Ridgeview Medical Center in Waconia.

The doctors admitted Julieanna for severe dehydration. They administered an IV, gave her a battery of tests to rule out pneumonia and bacterial infections, and kept her overnight. The physicians prodded and poked, but Julieanna hardly whimpered.

Flint stayed up all night, lying beside her baby on the hospital bed.

When Dr. Wuerger checked in the next morning, she knew that something was terribly wrong—she had never seen Julieanna so groggy and unresponsive. Wuerger called for a spinal tap.

The E.R. doc pierced Julieanna's spine with a long needle. The baby was so out of it that she could barely muster a soft moan in response. Flint had never seen her little girl so lethargic, and the sight of it scared her. She cried as the doctor withdrew the spinal fluid: a thick, yellow smear of pus.

"Brendalee, it doesn't look good," he said. "It's supposed to come out clear."

Julieanna's white blood cell count was 145,000—thousands of times higher than normal.

The doctor said something about meningitis and Children's Hospital in Minneapolis.

Brendalee felt confused.

"Your daughter is seriously ill," Wuerger told Flint. "We need to transport her to Children's—now!"

   

FLINT CALLED HER SISTER, and together they followed in Flint's car closely behind the ambulance carrying Julieanna to Minneapolis. The women phoned their family members with the bad news and rode the rest of the way in fear-filled silence.

At Children's, the doctors quarantined Julieanna in a double-doored isolation room in the pediatric intensive care unit. The little girl's body was dangerously hot. She was sensitive to light and noise. She lay on the big bed in the dark room, a heart monitor clipped to her toe and an IV in her arm.

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  • Bcwright 11/28/2011 11:25:00 PM

    @John Fryer, Apparently you read the article but didn't absorb much of it. Even if she got a bad lot of HIB vaccine, it was apparently not the cause of her hospital stay because the bad lot was contaminated with Bacillus cereus, not with HIB - they are two completely different types of bacteria. There are always a certain number of people who don't develop immunity when given a vaccine, because their immune systems are compromised in some way - which may also make it less likely for them to develop immunity even if they actually get the disease. But testing for this is almost never done unless there's a problem such as happened with this child - the cost of doing that for every vaccination would be prohibitive, and not particularly useful since there's nothing that can be done about it anyway. The entire rest of your screed is nothing but FUD - Fear, Uncertainty, and Doubt - that strings a lot of unrelated anecdotal stories together and asks repeated rhetorical questions. Why should anyone take you seriously?!

  • John Fryer 06/18/2009 2:03:00 AM

    Just read the whole article. How does this fit in to the vaccine schedules? Did she get the bad lot of hib vaccine mentioned? Presumably she had more than a dozen vaccines and today we know that not any of the vaccines worked for her. Why if the doctors are so clever did they make this error? I have in my life had less vaccines than this child but have survived. AIDS may or may not come from bad vaccines. One child in three neurologically ill may or may not come from bad vaccines. Every stop was pulled out to save this child but for most the doctors drugs and vaccines do appear to be untested for long term effects. One or two children in every thousand die and may or may not be because of vaccines. If you had a million examples of juju this would weigh evenly with SIDS in recent years. 12 million sick children is a new high in USA. Something is very very very wrong with USA health and that is FACT. No one of course has a clue? But as a chemist I was brought up to the constancy of properties. Some vaccines carry brain destroying chemicals DELIBERATELY added. If science is to be believed this means some people will have brain damage from vaccines. This child had "meningititis" but to a simple minded person she had a brain destroying problem. How can we know so much about Juju and meningitis and so little about SIDS, autism, ME, diabetes, epilepsy, AIDS etc etc? I read a similar counter case of a boy injected at ONE DAY and here again the doctors were wonderful in their effort to save him. In this case they failed. Again massive infections in every part of his body including his brain and no doubt that the vaccine KILLED him. Something SMELLS to me. But for me milk for babies and maybe vaccines when the child can COMPLAIN if they are BAD. To me I believe this child was harmed from the first vaccine and if they did not work we have confirmation every vaccine was counter productive for this girl.

  • Suzan Grovender 06/09/2009 8:01:00 PM

    It should be pointed out that this article demonstrates the serious problem of "journalism" which in fact is a promotion of half-truths in order to sell time on TV. Oprah and NBC and others are both guilty of shameless coverage of a topic for which they disregard the impact upon viewers who do not have medical or scientific education to reason through the need for immunization. I for one would not want to return to the days of polio run rampant, black wreathes on every other door as diphtheria moves through the neighborhood, chicken pox, mumps and measles a requirement of surviving (or not)childhood. I remember either having such disease or family members suffering through them. Having lived in those scary times changes one's value system of what is a risk worth taking with my child. Would I risk my child possibly getting autism over polio? Yes! Would I blatantly disregard the health of my community by not vaccinating? No. We in the modern world actually can make choices of life, death, or possible injury -- which in the case of immunizations is just what we are doing. We cannot be protected from all risks, so at least use the tools that can lead to the best outcome for most of us.

  • ronica 06/08/2009 11:44:00 PM

    First off I would like to start by saying that the people that written in have had some valid points and some not so much. I don't think People have took the time read the whole artical and know that JUJU is doing well and STILL ALIVE! Another one is that the dr never misdiagnosed JUJU she had only talk to the nurse on the phone. Befor she had brought JUJU in the ER. Only find out that She had it.This is my niece and I feel that before you make a comment you should really read the whole artical befor you say anything!

  • brendalee 06/08/2009 11:07:00 PM

    I am the nother of the chid in the article and am very confussed over some of the comments writen by viewers. It truly makes me sad to know that there are not more supporters out there trying to protect all of our child. If something like this happened to your child maybe your opinions would be different. We all make decisions if life for what we believe is right for our own children but what about everyone elses children? There are alot of children that are at high risk in getting preventable infectious desieses and unfortunatly people only care about what happens to their child. We only shared our story because we wanted everyone to know what can happen when a child goes unimmunized not what will happen. As far as the doctors go they were amazing and when you dont see an everyday illness you can just assume the worst

  • Dawn 06/06/2009 8:36:00 AM

    My sympathies, but my guess is that this child was vaccinated and this is what ultimately killed her - not the "super HIB mysterious bug". Vaccines weaken your immune system. Had this child not been previously vaccinated for other things, she would probably still be alive today.

  • Bob 06/05/2009 4:19:00 PM

    I was encouraged to read some of your comments: "if not, it seems like it would be a fruitful area of research.....and.."..its best for them to get no further vaccinations and to rely on herd immunity" Amen to those statements. "Is your position that, with the risk unknown, that they should assume the worst?" Do you think it is in the child's best interest to ignore the "unknown risk" and "assume the best"? I do hope you take the time and make the effort to read Richet's speech on anaphylaxis to learn the scientific improbability of creating a "one size fits all vaccine". After all, we can't create a "one size fits all" bike helmet or car seat...yet...for some reason that escapes me..our chldren are expected to accept a "one size fits all" vaccine.

  • Matthew Cline 06/05/2009 5:08:00 AM

    "You know, like take a child's birth-weight or premature delivery into account BEFORE injecting him with the HEP B within hours of birth?" I don't know if any research has been done into the relation between birth weight and prematureness and adverse reactions to vaccines given right after birth; if not, it seems like it would be a fruitful area of research. However, for children which are no longer in babyhood, there aren't any tests that can be done to determine the best individualized vaccine schedule for any given child, so for children who haven't had any adverse reactions to vaccines the "one size fits all" schedule is the best there is (for those children who *have* had an adverse reaction (or have a family history of such), it's best for them to get no further vaccinations and to rely on herd immunity). And as for the Amish: first, the concern about using the Amish to study the question of vaccine/autism connections isn't that they might have genes that make them more susceptible getting autism from vaccinations than the normal population, thus skewing the results, but that their genes might make them *less* susceptible to autism in *general*, regardless of being vaccinated or not, and that combined with their lower rates of vaccination would show a spurious correlation between low vaccination rates and low autism rates. Second, though the Amish *might* have genes that make them more susceptible to adverse reactions to vaccinations, they might have gens which make them *less* susceptible. Is your position that, with the risk unknown, that they should assume the worst? And finally, why are you putting scare-quotes around "genes"? Do you doubt that there's any genetic component to autism?

  • nhokkanen 06/05/2009 12:44:00 AM

    Adversomics: The Emerging Field of Vaccine Adverse Event Immunogenetics Gregory A. Poland, MD, Inna G. Ovsyannikova, PhD, and Robert M. Jacobson, MD The Pediatric Infectious Disease Journal Volume 28, Number 5, May 2009 SUMMARY We believe that adversomics (the immunogenetics and immunogenomics of vaccine adverse events at the individual and population level, respectively) is critical to understanding and preventing serious adverse vaccine-related events, developing the next generation of vaccines, and to improving public confidence in vaccine safety. Significant difficulties in the growth of the field of vaccine immunogenetics include the difficulty of studying large enough numbers of subjects (rare AEs are, by definition, rare), lack of research funding, the complexity and extensive polymorphic nature of immune response genes, statistical issues of multiple comparisons and statistical power, issues of multigenic and other gene interactions such as complementation and epigenetic DNA modifications, and gender, racial, and ethnic differences. Nonetheless, the field of adversomics is growing due to scientific interest in understanding the basis for vaccine reactions, �push� from the growing field of individualized medicine, and consumer demand for safer vaccines. The capability to reproduce statistical associations in independent population-based studies remains essential to assessing the generalization of such studies. Clearly more comprehensive studies are needed to determine if there are associations between genetic variations among individuals and susceptibility to serious adverse events in response to vaccination. These factors combined with technologic ability will lead to a new era in vaccinology and better, safer vaccines.

  • Bob Moffitt 06/05/2009 12:08:00 AM

    "First, there's not enough completely unvaccinated children around to perform such a study; see http://photoninthedarkness.com/?p=154. There have been studies of more-vaccinated vs less-vaccinated, which found no correlation." Read the "vaccinated vs. unvaccinated" study source you recommended. Just curious...are the Amish that DO vaccinate warned, PRIOR to vaccinating their children... their "genes" may not tolerate vaccines as well as other children? Is their "lifestyle" taken into account PRIOR to vaccination and the recommended vaccine schedule adjusted for it? Indeed, your "expert" unintentionally raises a very good question. He suggests "the only way to correctly do a study of vaccines and autism is to compare children who are matched for age, sex, geographic location, rural/urban/suburban setting, socio-economic group and race. That way, the only differences (we hope) would be vaccination status and autism prevalence" Do you recommend we do such a "comparision" of children BEFORE we inject them with a "one size fits all vaccine"? You know, like take a child's birth-weight or premature delivery into account BEFORE injecting him with the HEP B within hours of birth? Or are such precautions only required when seeking "unvaccinated" children to study? Here is a "source" that I think makes the point: http://tinyurl.com/3eey7p It is a Nobel Prize Award winning speech...given by Dr. Charles Richet almost one hundred years ago..wherein Dr. Richet observes that we are born with immune systems that are as unique to each individual as are their fingerprints and DNA.

  • Matthew Cline 06/04/2009 11:04:00 PM

    "It is long past time for public health officials to support pending federal legislation that seeks to fund a scientific, independent study of "vaccinated vs. unvaccinated" populations to ascertain, once and for all, if BOTH populations have suffered the same inexplicable increase in chronic autoimmune disorders. " First, there's not enough completely unvaccinated children around to perform such a study; see http://photoninthedarkness.com/?p=154. There have been studies of more-vaccinated vs less-vaccinated, which found no correlation. Second, the rise in autism rates is not inexplicable. There's two explanations: the broadening of the diagnostic criteria for autism, and diagnostic substitution (children who used to be diagnosed with other mental disorders are now instead be diagnosed with autism). I don't have a link handy, but there was a study in California which found that the percentage of children with "special needs" in public schools remained steady over the years, but the percentage with autism increased. Unless some inexplicable cause is decreasing the rates at which California children get mental disorders other than autism, the most likely explanation is diagnostic substitution. "Why blame the paretns who believe there is a connection between vaccines and autism etc when the child in this article was vaccinated and the vaccine was tainted." Because the baby/toddler is immunodeficient, meaning that both the vaccine didn't work and that she's more vulnerable to infection than a normal child. The more children who are unvaccinated, the greater the chance that she'll run into a child with some communicable disease and catch it.

  • Maurine Meleck 06/04/2009 10:05:00 PM

    I don't understand the jist of this article anyway. Why blame the paretns who believe there is a connection between vaccines and autism etc when the child in this article was vaccinated and the vaccine was tainted. It makes NO sense. Maurine Meleck

  • Paul G. King, PhD 06/04/2009 9:40:00 PM

    It never ceases to amaze me that a clear case of a doctor's failure to diagnose Haemophilous influenzae (Hi) of any serotype at an early stage and the concommittant harm caused to the child is somehow the UNDOCUMENTED failure of some other UNIDENTIFIED specific individual or individuals to vaccinate their children even, in cases like the lead one in this story, where no linkage to such other(s) can be established. Had the doctor initially proprerly tested for evidence of bacterial infection and the spectifc organism, then early intervention with the appropriate antibiotic would have probably resulted in a speedy rercovery of the child. Yet all the "balme" and "focus" is on a "witch hunt" against those who rightly hold that they have the right to decide which vaccines, if any, their children receive and when, if ever, they receive them. Moreover, the artoicle spends almost no "time" discussing the article's title, "Rare Hib disease increases in Minnesota", but does attempt to lay the blame for the medical malpractice that Brendalee Flint initially received not at the initial treating physcian's door where it apparently belongs but rather at the door of some unidentified and unidentifiable group ("the anti-vaccine movement"). Factually, there is no "the anti-vaccine movement" in Minnesota -- if there were such, then, like the real and identifiable "anti-abortion movement", at a minimum, there would be groups of people picketing every major pediatric practice in Minnessota -- and there appear to be none. Thus, the "the anti-vaccine movement" is just another straw man designed to deflect public attention from the very real problem that our current vaccines are, as a group, neither safe enough, nor effective enough nor, in almost every case, truly cost effective enough, and the medical establishment, public health officials, the government and the vaccine makers are quite content with these realities. This article is simply propagandistic yellow journalism. If any wish to see the time-related reality of the negative effects of a vaccine that only covers one serotype (Hi B) of a multi-serotype bacteria (Hi), then you can go to the website: http:/www.mercury-freedrugs.org and, in the "Documents" section, open "A Draft Review of: 'Florida Governor' Task Force on Autism Spectrum Disorders- Task Force Requests to the Florida DoH', Part 1 (17 October 2008; 68 pages)", and read the section starting at the bottom of page R-7, which uses the CDC's published data and other studies to discuss the Hib vaccine. Hopefully, the information provided will be helpful and, perhaps, it may encourage you to read the entire draft report.

  • sarah jane 06/04/2009 8:10:00 PM

    How many scientific studies will be enough to convince parents that autism is not caused by vaccines. There is not an unlimited pot of gold out there to conduct research for autism causes and we have spent more than enough on a witch hunt begun by Andrew Wakefield based on falty data and perpetuated by washed up ex-playboy models. How can anyone advocate for a large study of unvaccinated children...who on earth is crazy enough to think that thousands of children should be placed at risk of serious diseases by remaining unvaccinated? dozens of credible studies have been conducted on the vaccine/autism connection - all of which deem that vaccines are safe..enough is enough - children are not indespensible!

  • Bob Moffitt 06/04/2009 5:42:00 PM

    It is long past time for public health officials to support pending federal legislation that seeks to fund a scientific, independent study of "vaccinated vs. unvaccinated" populations to ascertain, once and for all, if BOTH populations have suffered the same inexplicable increase in chronic autoimmune disorders. It defies common sense that public health officials hve not yet done this study...especially if their vaccines are as safe and harmless as they insist they are.

  • Maurine Meleck 06/04/2009 5:03:00 PM

    Considering I grew up in Minneapolis, this artilce is doubly disturbing. You have thislenghty story of a child who contracted a disease in childhood. It's alwasy sad when children get sick. Here is a comprable story. My graandchild was a healthy, neurotypcal baby, talking, laughing, responding until about the age of 2(or close to it) Then suddenly he was gone-crying all the time, making no eye contact, tantrumming all day and diagnosed autistic before age 3. Tests showed he had oxidative stress, mitochondrial dysfunction, immune disorder, gut dysbiosis, allergies to dozens of foods and the list goes on. He had all of his vaccines, just like the doctors said he needed them. We did what we were supposed to do so don't blame us for no longer vaccinating them. Yes, many say vaccines aren't the cause. What is????????? They have no answer. been a puzzle to so many for over a decade. It's not a puzzle to us. His younger brother also had it, but he is totally recovered through bio-medical treatments. You can believe Paul Offit, who makes a fortune from vaccines or the big drug companies who do the same and the CDC that both mandates vaccines and carries on their safety studies or you can believe tens of thousands of parents who saw their normally developing children suddenly disappear into autism. Which is it???? Maurine Meleck North Augusta, SC

  • Pareidolius 06/04/2009 1:40:00 AM

    In a sea of fear-based, magical-thinking regarding vaccine safety, your article was breath of fresh air.

 

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